0.1–0.2 µm Nylon filters
Fine-pore configurations for applications requiring a high level of particulate retention. Where microbial or sterile performance is required, the exact filter grade and validation documentation must be confirmed.
Nylon Membrane Capsule Filter – 0.1 to 3.0 µm
Filtra International supplies hydrophilic Nylon membrane capsule filters for precision filtration of aqueous solutions, alcohol-containing liquids and compatible process fluids. Available pore sizes range from 0.1 to 3.0 µm, with multiple capsule lengths and connection configurations for laboratory, pilot and process filtration.
Nylon combines natural hydrophilicity with documented alcohol resistance, making it particularly useful where aqueous and alcohol-based liquids need to be filtered using the same general membrane chemistry.
Membrane
Hydrophilic Nylon
Pore sizes
0.1–3.0 µm
Liquid type
Aqueous & alcohol
Compact filter area
Approx. 300 cm²*
*Configuration note: approximately 300 cm² is documented for the compact Nylon capsule configuration. Filtra also offers larger selectable capsule formats; filtration area and other technical properties vary with the exact capsule size and configuration.
Nylon capsule filter technical overview
| Filter type | Disposable Nylon membrane capsule filter for liquid filtration |
|---|---|
| Filter membrane | Hydrophilic Nylon |
| Membrane characteristics | Hydrophilic, alcohol resistant and low protein adsorption |
| Media support | Polypropylene |
| Capsule hardware / housing | Polypropylene |
| Optional filling bell | Polycarbonate, configuration-dependent |
| Available pore sizes | 0.1, 0.2, 0.45, 0.65, 1.0 and 3.0 µm |
| Filtra selectable capsule lengths | 1.5", 2.5", 5", 10" and 20" |
| Compact configuration filter area | Approx. 300 cm² |
| Compact configuration maximum working pressure | 5 bar at 20 °C |
| Documented maximum operating temperature | 80 °C |
| Integrity testing | 100% integrity tested for the documented compact capsule range |
| Biological safety | Documented components meet USP Class VI-121°C specifications for plastics |
| Hot-water sanitisation | 90 °C for 30 minutes, multiple cycles |
| Autoclaving | 121 °C for 30 minutes, multiple cycles for the documented compact configuration |
| Material compliance | Documented FDA 21 CFR and EU 10/2011 food-contact material compliance |
How does a Nylon membrane capsule filter work?
Process liquid enters the capsule through the selected inlet connection and passes through the Nylon membrane. The controlled membrane pore structure retains particulate contamination according to the selected pore-size rating, while filtered liquid exits through the outlet connection.
The membrane and housing form one enclosed disposable assembly, so no separate reusable cartridge housing is required for the capsule itself. This simplifies filter replacement in laboratory, pilot and small-process filtration systems.
Why choose a hydrophilic Nylon membrane?
Nylon is naturally hydrophilic, allowing aqueous liquids to wet the membrane readily. The documented membrane also combines this hydrophilic behaviour with alcohol resistance, which makes Nylon particularly interesting for compatible aqueous and alcohol-containing process fluids.
The membrane is also documented as having low protein adsorption. However, membrane selection for valuable proteins or biological products should still be based on actual compatibility and recovery testing rather than membrane material alone.
0.1 to 3.0 micron Nylon capsule filters
Six selectable pore sizes allow the Nylon capsule to cover different fine filtration and clarification requirements.
0.45–0.65 µm Nylon filters
Common fine-filtration ratings for clarification, laboratory filtration and compatible aqueous or alcohol-containing solutions.
1.0–3.0 µm Nylon filters
Larger-pore configurations for particulate reduction and clarification where higher solids loading or lower flow resistance is required.
Available ratings are 0.1, 0.2, 0.45, 0.65, 1.0 and 3.0 µm. Selection should consider required retention, solids loading, liquid compatibility and allowable pressure drop.
Nylon capsule filters for aqueous and alcohol-based liquids
Nylon membrane capsules are especially relevant when the process includes water-based liquids, alcohol-containing solutions or compatible solvent mixtures.
Typical use can include laboratory analysis, sample preparation, process development and fine filtration of compatible aqueous or alcohol-based process fluids.
Chemical compatibility: “alcohol resistant” should not be interpreted as universal compatibility with every organic solvent or chemical. Confirm membrane and housing compatibility against the actual liquid, concentration, temperature and exposure time.
Nylon capsule filter connection options
The current Filtra Nylon capsule range includes multiple inlet and outlet options for integration into laboratory tubing, pilot equipment and process systems.
| NPT | 1/4" NPT male, 3/8" NPT male, 1/2" NPT male and 3/8" NPT female options |
|---|---|
| Swagelok | 1/4", 5/16", 3/8" and 1/2" selectable connection options |
| CPC quick-connect | 1/4" CPC PLC male and female configurations |
| Hose barb | 3/8", 1/2" and 1/4"–3/8" stepped hose-barb options |
| Sanitary connection | 1" Tri-Clamp / Tri-Clover |
Exact fitting availability can depend on capsule size and configuration. Confirm the inlet and outlet combination required for the installation.
Nylon capsule lengths from 1.5 to 20 inches
Filtra's current selectable Nylon capsule configurations include 1.5", 2.5", 5", 10" and 20" lengths.
Larger capsule formats can provide increased filtration area and throughput, but the documented 300 cm² specification belongs to the compact capsule configuration and should not be applied automatically to every larger size.
Typical Nylon capsule filter applications
- Laboratory sample preparation
- Aqueous-solution filtration
- Alcohol-containing liquid filtration
- Compatible solvent filtration
- Fine particle removal
- Liquid clarification
- Laboratory analysis
- Pilot-scale filtration
- Pharmaceutical research and process development
- Biotechnology laboratory filtration
Nylon vs PES and PVDF capsule filters
| Nylon | PES | PVDF | |
|---|---|---|---|
| Wettability | Hydrophilic | Hydrophilic | Hydrophilic |
| Key selection feature | Alcohol resistance | Strong hydrophilicity and low protein adsorption | Low protein adsorption |
| Typical starting point | Aqueous and compatible alcohol-based liquids | Aqueous process liquids and buffers | Protein-sensitive and compatible process liquids |
| Final selection | Confirm chemical compatibility, retention requirement, product recovery and process conditions for the actual liquid. | ||
Integrity Testing, Biological Safety & Material Compliance
The documented compact Nylon capsule range includes several quality and material characteristics relevant to laboratory, biotechnology and process filtration.
100% integrity tested
The documented compact Nylon capsule range is individually integrity tested
during manufacturing.
USP Class VI
Documented components meet biological-safety specifications for
USP Class VI-121°C plastics.
Autoclave compatible
The documented compact configuration supports autoclaving at
121 °C for 30 minutes over multiple cycles.
Material compliance
Documented construction materials have FDA 21 CFR and EU 10/2011
food-contact material compliance.
These specifications apply to the documented capsule configuration. Requirements for regulated pharmaceutical processes should be confirmed against the exact membrane grade, size and supporting documentation.
Nylon capsule filters for pharmaceutical and biotechnology development
Nylon capsules can be useful in pharmaceutical R&D, biotechnology laboratories and pilot-scale filtration where the process liquid is chemically compatible with the membrane.
For regulated sterile or bioburden-reduction processes, a nominal 0.2 µm Nylon membrane should not automatically be treated as sterilizing grade. The applicable retention validation, integrity-test limits and product documentation must be confirmed for the exact filter grade.
How to select a Nylon capsule filter
Correct selection should consider the complete liquid and process conditions.
- Required pore size from 0.1 to 3.0 µm
- Aqueous, alcohol-containing or other compatible process liquid
- Alcohol concentration and chemical composition
- Required particle-retention level
- Required flow rate
- Total batch or process volume
- 1.5", 2.5", 5", 10" or 20" capsule format
- NPT, Swagelok, CPC, hose-barb or Tri-Clamp connection
- Operating pressure and temperature
- Sanitisation or autoclaving requirements
- Pharmaceutical documentation requirements where applicable
Compare Nylon with other capsule filter membranes
Not sure whether Nylon, PES, PVDF or PTFE is the best membrane for your liquid? Send us the fluid composition, pore size, process volume and connection requirements for technical selection support.
Nylon Membrane Capsule Filter FAQ
What is a Nylon membrane capsule filter?
A Nylon membrane capsule filter is a self-contained disposable filter containing a hydrophilic Nylon membrane inside a polymer capsule. It is used for fine filtration and clarification of compatible aqueous, alcohol-containing and process liquids.
Is a Nylon membrane hydrophilic?
Yes. The documented Nylon membrane is naturally hydrophilic and can therefore wet readily with compatible aqueous liquids without hydrophobic-membrane pre-wetting.
Can Nylon capsule filters be used with alcohol?
Yes. The documented Nylon membrane combines hydrophilicity with alcohol resistance and is suitable for compatible aqueous and alcohol-based liquids. Compatibility should still be checked for the specific alcohol concentration, temperature and process conditions.
Which pore sizes are available?
Available Nylon capsule pore sizes include 0.1, 0.2, 0.45, 0.65, 1.0 and 3.0 µm.
Is a 0.2 micron Nylon capsule filter available?
Yes. A 0.2 µm Nylon configuration is available. A 0.2 µm pore size alone, however, should not be interpreted as proof of validated sterilizing-grade performance.
Which Nylon capsule lengths are available?
Filtra currently offers 1.5-inch, 2.5-inch, 5-inch, 10-inch and 20-inch selectable Nylon capsule configurations.
What connection types are available?
Current Filtra options include NPT, Swagelok, CPC quick-connect, hose-barb and 1-inch Tri-Clamp / Tri-Clover connections.
What is the filtration area of a Nylon capsule filter?
The documented compact Nylon capsule configuration provides approximately 300 cm² of filtration area. Larger capsule configurations can have different effective filtration areas.
Can Nylon capsule filters be autoclaved?
The documented compact Nylon capsule configuration supports autoclaving at 121 °C for 30 minutes over multiple cycles. Confirm the limit for the exact capsule configuration selected.
Are Nylon capsule filters integrity tested?
The documented compact Nylon capsule range is 100% integrity tested during manufacturing. For regulated applications, confirm the test method and acceptance specification for the exact selected configuration.