Single-use bioprocessing products provide configurable fluid paths for sterile transfer, sampling, filling, filtration, cell culture and pharmaceutical processing. The range includes single-use assemblies, process bags, bottle assemblies, tubing sets, freeze bags, aseptic connectors and quick couplings.
Systems can be configured around the required process, connection type, tubing, container and sterilisation method. This allows engineers to specify disposable bioprocess systems for both simple fluid-transfer duties and more complex closed processing applications.
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Single-Use Fluoropolymer Freeze Bag Assembly -
Custom Single-Use Bioprocess Bag Assemblies -
Custom Single-Use Bottle Assemblies -
Pharmaceutical Process Hose Assembly -
High-Flow Genderless Sterile Connector -
Reinforced Braided Silicone Tubing for Bioprocessing -
Plastic Hose Barb Fittings for Bioprocessing -
Plastic Tri-Clamp Adapter with Integrated Gasket -
Non-Invasive Bubble Detector for Bioprocess Tubing -
Reusable Freeze Bag Protection Cassette -
Portable Filter Integrity Tester it-02 – Bubble Point, Diffusion & WFT -
Custom Single-Use PUPSIT Assemblies -
Aseptic Single-Use Sampling Assemblies -
Single-Use Bioreactor Bags -
Single-Use Mixing Bags for Bioprocessing -
Custom Single-Use Filling Assemblies -
Single-Use Freeze-Thaw Bags -
Polypropylene (PP) Capsule Filter – Absolute Rated | 0.3–50 µm -
SIP PTFE Capsule Filter for Sterile Air, Gas & Vent Filtration -
Nylon Membrane Capsule Filter – 0.1 to 3.0 µm | Aqueous & Alcohol Filtration -
PVDF Membrane Capsule Filter – Low Protein Adsorption | 0.1–3.0 µm -
PTFE Capsule Filter – Hydrophobic Membrane | 0.05–0.65 µm -
PES Membrane Capsule Filter – Hydrophilic | 0.03–5.0 µm -
Sterile & Aseptic Connectors for Single-Use Bioprocessing
Single-Use Bioprocessing
Configurable fluid-path solutions for pharmaceutical processing
Single-use bioprocessing systems combine disposable tubing, process bags, bottles, connectors and other fluid-contact components into a defined fluid path for pharmaceutical and biotechnology applications.
Systems can be configured for sterile fluid transfer, sampling, filtration, filling, cell culture, product handling, storage and other upstream or downstream process operations. Instead of relying on one fixed assembly, components can be selected around the technical requirements of the process.
Product Configuration
Build the fluid path around the application
A single-use assembly can range from a relatively simple tubing line to a multi-branch fluid handling system incorporating containers, connectors, filters and multiple process interfaces.
01
Single-use bag assemblies
Flexible bag systems can combine process bags with tubing, connectors, filters and other components for fluid transfer, storage, sampling, buffer handling and bioprocess applications.
02
Single-use bottle assemblies
Bottle-based systems combine a process container with the required tubing and connection points for sampling, filling, transfer, media handling, product collection or storage.
03
Single-use tubing assemblies
Preconfigured tubing sets provide a defined connection between process equipment, vessels, filters, bags and bottles and can include branches, clamps, couplings and other fluid-path components.
04
Aseptic connection systems
Sterile connectors and quick couplings can be incorporated where independent tubing or process assemblies need to be connected or disconnected as part of a controlled fluid-handling process.
Process Applications
Single-use systems throughout the bioprocess
Disposable fluid paths are used across pharmaceutical manufacturing and biotechnology processes. The required configuration depends on how the fluid is being transferred, processed, sampled, filtered, filled or stored.
Sterile fluid transfer
Aseptic sampling
Sterile filtration
Filling
Cell culture
Upstream processing
Downstream processing
Buffer handling
Media transfer
Product transfer
Single-use manifolds
Bioreactor connections
Freeze & storage
Operating Principle
A defined disposable fluid path
In a single-use bioprocessing system, the wetted process pathway is created from compatible disposable components. A process liquid may travel from a vessel through tubing, connectors, filters or manifolds before entering another process system, bag or bottle.
The arrangement is determined by the application. A sampling assembly may connect a process line to one or more collection containers, while a filtration or filling assembly may incorporate multiple branches, longer tubing runs, filtration components and different process connections.
This configuration-based approach allows engineers to define the fluid path according to the process rather than selecting only from fixed catalogue assemblies.
Connection Technology
Connecting the complete fluid path
Connection components are selected according to tubing dimensions, process interfaces, sterilisation requirements and the way different parts of the fluid path need to be connected during operation.
Aseptic & sterile connectors
Used to join separate fluid paths where a controlled or sterile connection is required. Connector geometry and connection method are selected for the intended process configuration.
Quick disconnect couplings
Designed for practical connection and disconnection between tubing sections. Different connection sizes and flow-path arrangements can be incorporated depending on the application.
Clamps & tubing interfaces
Clamps and tubing connections mechanically secure sections of the assembly and can be selected around tubing size, fitting geometry and process requirements.
Freeze, Storage & Transport
Single-use solutions beyond fluid transfer
Single-use process bags can also be configured for freezing and storage of process liquids. Suitable systems combine the flexible container with tubing and connection components required before or after the freezing step.
Mechanical protection can be added around the bag where additional support is required during freezing, handling, storage or transport. Protective systems can help support the bag and reduce direct mechanical loading on flexible film, tubing and connection points.
Freeze bag configurations
Freeze bags and protective support systems can form part of a wider single-use process configuration, connecting frozen storage with upstream or downstream fluid-handling steps.
Materials & Sterilisation
Compatibility is determined by the final configuration
Single-use systems can incorporate pharmaceutical-grade polymer components, flexible tubing, process containers and plastic connection technology. Container materials may include materials such as polycarbonate, PETG, PFA and FEP where appropriate for the selected component.
The required sterilisation method must be considered when selecting the complete fluid path. Depending on the components used, configurations may be suitable for gamma irradiation, autoclaving or another appropriate sterilisation approach.
Configuration-specific documentation
Material declarations, regulatory documentation, sterilisation compatibility, extractables and leachables information, biological safety data and traceability documentation depend on the individual components incorporated into the final assembly. Requirements should therefore be defined during specification rather than assumed for every product within the collection.
System Specification
How to specify a custom single-use assembly
The most efficient starting point is the process itself. An existing assembly drawing, component specification or even a simplified process sketch can be used to determine the required fluid-path configuration.
01
Define the application
Specify whether the assembly is required for transfer, sampling, filtration, filling, storage, cell culture or another process step.
02
Define the fluid path
Identify the required tubing dimensions, connection points, container type and volume, together with filters, clamps, valves or other components.
03
Define the operating conditions
Relevant information may include the process fluid, temperature, pressure, flow conditions, sterilisation method and required handling or storage conditions.
04
Provide a drawing or existing specification
A technical drawing, component list or process sketch provides a useful basis for reviewing the assembly and selecting suitable fluid-path components.
Frequently Asked Questions
Single-use bioprocessing FAQ
What is a single-use bioprocessing system?
A single-use bioprocessing system is a disposable fluid path made from components such as tubing, process bags, bottles, connectors, filters and couplings. These systems are used for pharmaceutical and biotechnology operations including transfer, sampling, filtration, filling and storage.
Can single-use assemblies be customised?
Yes. Assemblies can be configured around the application, tubing dimensions, container type, process connections, sterilisation method and additional components required within the fluid path.
What are single-use assemblies used for?
Typical applications include sterile fluid transfer, process sampling, filtration, pharmaceutical filling, buffer and media handling, upstream and downstream processing, cell culture, manifolds and bioreactor connections.
What is an aseptic connector?
An aseptic connector is used to join separate fluid paths where maintaining a controlled sterile boundary is required. The appropriate connector depends on the tubing, process conditions and connection procedure.
Can single-use assemblies be sterilised?
Depending on the components selected, assemblies may be configured for sterilisation methods such as gamma irradiation or autoclaving. Compatibility must be assessed for all components within the final assembly.
What information is required to specify a single-use assembly?
Useful information includes the process application, process fluid, tubing material and dimensions, container volume, required connectors, filters or other components, operating conditions, sterilisation method, quantity and required documentation. A technical drawing or process sketch is also helpful where available.
Assembly Specification Request
Configure a single-use assembly for your process
Provide the information currently available about your process, required fluid path and operating conditions. A complete technical specification is not required at this stage. Existing drawings, specifications or process sketches can also be used as the starting point for configuration.