{"product_id":"reusable-freeze-bag-protection-cassette","title":"Reusable Freeze Bag Protection Cassette","description":"\u003ch2\u003eProduct description\u003c\/h2\u003e\n\n\u003cp\u003e\n  Reusable freeze bag protection cassettes are designed to protect\n  single-use pharmaceutical bags during freezing, frozen storage and\n  transportation. The rigid metal enclosure supports the bag, tubing\n  and process connections and helps reduce the risk of mechanical\n  damage at very low temperatures.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  The cassette is individually configured around the specific bag,\n  tubing layout and connectors. Standard configurations can accommodate\n  single-use bags from approximately 5 mL to 2 L, with larger sizes\n  available for custom applications.\n\u003c\/p\u003e\n\n\n\u003ch3\u003eTechnical overview\u003c\/h3\u003e\n\n\u003cp\u003e\n  Flexible single-use bags and tubing become more vulnerable to\n  mechanical stress when frozen. A rigid protection cassette provides\n  external support to the assembly and limits movement during freezing,\n  storage, handling and transport.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Internal form elements can be designed around the bag and fluid-path\n  geometry to secure the container, tubing and connectors. This is\n  particularly relevant for assemblies incorporating larger sterile\n  connectors or other components that require defined positioning.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  The reusable metal construction is suitable for pharmaceutical\n  environments and can be cleaned between uses. Aluminum, stainless\n  steel and electropolished stainless-steel configurations are available.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eOperating principle\u003c\/h2\u003e\n\n\u003cp\u003e\n  The single-use bag assembly is placed inside the rigid cassette before\n  freezing. Internal contours and retaining features position the bag,\n  tubing and connectors so that movement is restricted during handling\n  and transportation.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  As the product freezes, the cassette provides mechanical support around\n  the flexible assembly. This helps protect the bag and connection points\n  from impact, vibration and uncontrolled movement while the product is\n  in a frozen and potentially more fragile condition.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Depending on the freezing process, the cassette can be supplied with\n  openings in the housing to increase airflow around the bag or with a\n  closed housing where additional enclosure is preferred.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  The flat cassette geometry is suitable for conventional freezer storage\n  and can also be configured for use with plate-freezing equipment.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eMaterial options\u003c\/h2\u003e\n\n\u003cp\u003e\n  Freeze bag protection cassettes are manufactured from metal rather\n  than disposable polymer materials. Available constructions include:\n\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003e\u003cstrong\u003eAluminum\u003c\/strong\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cstrong\u003eStainless steel\u003c\/strong\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cstrong\u003eElectropolished stainless steel\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\n  Standard surfaces can be supplied cleaned and degreased, while\n  electropolished surfaces are available where a more refined stainless\n  steel surface is required.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  The appropriate material should be selected according to handling,\n  cleaning, freezer environment, required durability and site-specific\n  operational requirements.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eAvailable micron ratings\u003c\/h2\u003e\n\n\u003cp\u003e\n  \u003cstrong\u003eNot applicable.\u003c\/strong\u003e A freeze bag protection cassette is\n  a mechanical handling and storage component and does not contain\n  filtration media. It therefore has no micron or pore-size rating.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  If the associated single-use assembly contains filtration components,\n  filter membrane and micron rating are specified separately as part of\n  the fluid-path configuration.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eDesign and construction\u003c\/h2\u003e\n\n\u003cp\u003e\n  Each cassette is configured around the required single-use bag and its\n  associated tubing and connection technology. The internal geometry can\n  therefore be adapted to the actual assembly rather than relying on a\n  universal cavity.\n\u003c\/p\u003e\n\n\n\u003ch3\u003eBag size range\u003c\/h3\u003e\n\n\u003cp\u003e\n  Standard configurations are suitable for bag volumes from approximately\n  5 mL up to 2 L.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Typical supported volumes include:\n\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003e5 mL\u003c\/li\u003e\n  \u003cli\u003e50 mL\u003c\/li\u003e\n  \u003cli\u003e100 mL\u003c\/li\u003e\n  \u003cli\u003e250 mL\u003c\/li\u003e\n  \u003cli\u003e500 mL\u003c\/li\u003e\n  \u003cli\u003e1 L\u003c\/li\u003e\n  \u003cli\u003e2 L\u003c\/li\u003e\n  \u003cli\u003eLarger or custom bag sizes on request\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\n\u003ch3\u003eTemperature capability\u003c\/h3\u003e\n\n\u003cp\u003e\n  The cassette is designed for pharmaceutical freezing applications at\n  temperatures down to approximately \u003cstrong\u003e−85°C and below\u003c\/strong\u003e.\n  Suitability of the complete system must also consider the bag film,\n  tubing, connectors and frozen product.\n\u003c\/p\u003e\n\n\n\u003ch3\u003ePerforated and closed designs\u003c\/h3\u003e\n\n\u003cp\u003e\n  Two principal housing concepts can be considered depending on the\n  freezing and transport process.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  \u003cstrong\u003ePerforated or slotted housings\u003c\/strong\u003e allow increased air\n  circulation around the bag and can support efficient heat transfer\n  during freezing.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  \u003cstrong\u003eClosed housings\u003c\/strong\u003e provide a more enclosed cassette\n  construction and can help prevent materials such as dry-ice granulate\n  from entering the cassette during transport.\n\u003c\/p\u003e\n\n\n\u003ch3\u003eBag, tubing and connector protection\u003c\/h3\u003e\n\n\u003cp\u003e\n  Internal contours can be designed to locate the bag and secure tubing\n  and process connections. This helps prevent components from moving\n  freely within the cassette during freezing, storage and transportation.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Configurations can also accommodate relatively large sterile connectors\n  and other fluid-path components where sufficient internal space and\n  mechanical protection are required.\n\u003c\/p\u003e\n\n\n\u003ch3\u003eTechnical construction details\u003c\/h3\u003e\n\n\u003ctable style=\"width:100%; border-collapse:collapse; margin:24px 0;\"\u003e\n  \u003ctbody\u003e\n    \u003ctr\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        \u003cstrong\u003eBag volume range\u003c\/strong\u003e\n      \u003c\/td\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        Approx. 5 mL to 2 L, larger sizes on request\n      \u003c\/td\u003e\n    \u003c\/tr\u003e\n\n    \u003ctr\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        \u003cstrong\u003eTemperature\u003c\/strong\u003e\n      \u003c\/td\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        Down to approximately −85°C and below\n      \u003c\/td\u003e\n    \u003c\/tr\u003e\n\n    \u003ctr\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        \u003cstrong\u003eMaterials\u003c\/strong\u003e\n      \u003c\/td\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        Aluminum, stainless steel\n      \u003c\/td\u003e\n    \u003c\/tr\u003e\n\n    \u003ctr\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        \u003cstrong\u003eSurface\u003c\/strong\u003e\n      \u003c\/td\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        Cleaned and degreased; electropolished option available\n      \u003c\/td\u003e\n    \u003c\/tr\u003e\n\n    \u003ctr\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        \u003cstrong\u003eSheet thickness\u003c\/strong\u003e\n      \u003c\/td\u003e\n      \u003ctd style=\"padding:10px; border-bottom:1px solid #eee;\"\u003e\n        Approx. 0.5–2.0 mm\n      \u003c\/td\u003e\n    \u003c\/tr\u003e\n\n    \u003ctr\u003e\n      \u003ctd style=\"padding:10px;\"\u003e\n        \u003cstrong\u003eDimensional tolerances\u003c\/strong\u003e\n      \u003c\/td\u003e\n      \u003ctd style=\"padding:10px;\"\u003e\n        According to DIN ISO 2768-cK\n      \u003c\/td\u003e\n    \u003c\/tr\u003e\n  \u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\n\u003ch3\u003eIdentification and handling options\u003c\/h3\u003e\n\n\u003cp\u003e\n  Cassettes can be individually laser marked with identification such\n  as part numbers or QR codes. Sealing options can also be incorporated\n  where required for handling or traceability.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Dedicated freezer inserts, racks, holders and transport systems can\n  also be developed to accommodate multiple cassettes within a common\n  storage or logistics system.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eTypical applications\u003c\/h2\u003e\n\n\u003cp\u003e\n  Freeze bag protection cassettes are intended for pharmaceutical and\n  biotechnology processes where frozen product must be stored or\n  transported in flexible single-use bags.\n\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003eDrug substance freezing\u003c\/li\u003e\n  \u003cli\u003eFrozen drug substance storage\u003c\/li\u003e\n  \u003cli\u003eFrozen pharmaceutical intermediate storage\u003c\/li\u003e\n  \u003cli\u003eCell and gene therapy processes\u003c\/li\u003e\n  \u003cli\u003eVaccine storage\u003c\/li\u003e\n  \u003cli\u003eCryogenic and low-temperature process handling\u003c\/li\u003e\n  \u003cli\u003eSingle-use freeze bag protection\u003c\/li\u003e\n  \u003cli\u003eFrozen product transportation\u003c\/li\u003e\n  \u003cli\u003eDry ice transportation\u003c\/li\u003e\n  \u003cli\u003ePlate freezer applications\u003c\/li\u003e\n  \u003cli\u003eConventional freezer storage\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eKey benefits\u003c\/h2\u003e\n\n\u003cul\u003e\n  \u003cli\u003e\n    \u003cstrong\u003eMechanical protection:\u003c\/strong\u003e\n    provides a rigid enclosure around flexible single-use bags,\n    tubing and connectors.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eLow-temperature capability:\u003c\/strong\u003e\n    designed for pharmaceutical applications at approximately\n    −85°C and below.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eApplication-specific design:\u003c\/strong\u003e\n    the internal geometry can be configured around the actual\n    bag assembly and connection layout.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eConnector protection:\u003c\/strong\u003e\n    internal contours can accommodate and secure larger sterile\n    connectors and other fluid-path components.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eReusable metal construction:\u003c\/strong\u003e\n    aluminum and stainless-steel cassettes can be cleaned and reused.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eDifferent freezing concepts:\u003c\/strong\u003e\n    perforated and closed housing configurations are available.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eFlexible freezer integration:\u003c\/strong\u003e\n    the flat design can be considered for conventional freezers\n    and plate-freezing systems.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eIdentification options:\u003c\/strong\u003e\n    laser marking with part numbers or QR codes can be incorporated.\n  \u003c\/li\u003e\n\u003c\/ul\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eConfiguration and quotation\u003c\/h2\u003e\n\n\u003cp\u003e\n  Freeze bag protection cassettes are normally configured around the\n  actual bag assembly rather than selected only by nominal bag volume.\n  Bag dimensions, tubing routing and connector geometry all influence\n  the final cassette design.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  For technical configuration and quotation, provide the following\n  information where available:\n\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003eBag manufacturer or bag drawing\u003c\/li\u003e\n  \u003cli\u003eNominal bag volume\u003c\/li\u003e\n  \u003cli\u003eFilled bag dimensions\u003c\/li\u003e\n  \u003cli\u003eBag film construction where relevant\u003c\/li\u003e\n  \u003cli\u003eTubing dimensions and routing\u003c\/li\u003e\n  \u003cli\u003eConnector types and dimensions\u003c\/li\u003e\n  \u003cli\u003eRequired minimum storage temperature\u003c\/li\u003e\n  \u003cli\u003eFreezing method\u003c\/li\u003e\n  \u003cli\u003eConventional freezer or plate freezer\u003c\/li\u003e\n  \u003cli\u003eStorage and transport method\u003c\/li\u003e\n  \u003cli\u003eDry ice transport requirement\u003c\/li\u003e\n  \u003cli\u003ePreferred cassette material\u003c\/li\u003e\n  \u003cli\u003ePerforated or closed housing\u003c\/li\u003e\n  \u003cli\u003eSurface-finish requirement\u003c\/li\u003e\n  \u003cli\u003eLaser marking or QR-code requirement\u003c\/li\u003e\n  \u003cli\u003eRack or multi-cassette handling requirement\u003c\/li\u003e\n  \u003cli\u003ePrototype quantity\u003c\/li\u003e\n  \u003cli\u003eEstimated annual demand\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\n  Where no existing cassette design is available, a bag drawing or\n  physical bag assembly can provide the starting point for developing\n  a suitable protection system.\n\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is a freeze bag protection cassette?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"A freeze bag protection cassette is a rigid reusable enclosure designed to support and protect pharmaceutical single-use bags, tubing and connectors during freezing, frozen storage and transportation.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What bag sizes can be used in a freeze protection cassette?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Standard configurations can accommodate single-use bags from approximately 5 mL up to 2 L. Larger custom bag sizes can also be considered.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What temperatures can a pharmaceutical freeze cassette withstand?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"The cassette is designed for pharmaceutical freezing applications at temperatures down to approximately -85°C and below.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What materials are available for freeze bag protection cassettes?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Available materials include aluminum and stainless steel, with electropolished stainless-steel surface options available where required.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is the difference between perforated and closed freeze cassettes?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Perforated or slotted housings increase airflow around the bag during freezing, while closed housings provide a more enclosed design and can help prevent materials such as dry-ice granulate from entering the cassette.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can a freeze cassette be designed around a custom bag assembly?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes. The cassette can be configured around the specific bag, tubing layout and connector geometry so that the complete assembly is supported during freezing, storage and transportation.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Filtra International","offers":[{"title":"5 mL \/ Aluminum \/ Perforated \/ Slotted","offer_id":57319571620166,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":true},{"title":"5 mL \/ Aluminum \/ Closed \/ Non-Perforated","offer_id":57319571652934,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":true},{"title":"5 mL \/ Aluminum \/ Custom \/ To Be Specified","offer_id":57319571685702,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":true},{"title":"5 mL \/ Stainless Steel \/ Perforated \/ Slotted","offer_id":57319571718470,"sku":null,"price":0.0,"currency_code":"EUR","in_stock":true},{"title":"5 mL \/ Stainless Steel \/ Closed \/ 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