{"product_id":"single-use-tubing-assemblies","title":"Custom Single-Use Tubing Assemblies","description":"\u003ch2\u003eProduct description\u003c\/h2\u003e\n\n\u003cp\u003e\n  Custom single-use tubing assemblies are preconfigured disposable fluid paths\n  for pharmaceutical and bioprocess applications. They combine process tubing\n  with the required connectors, couplings, clamps, filters, sanitary interfaces\n  and other components into an application-specific assembly.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Assemblies can be supplied sterile and ready-to-use or as non-sterile tubing\n  systems. The tubing material, connection technology and sterilisation method\n  are selected according to the process requirements and intended operating\n  conditions.\n\u003c\/p\u003e\n\n\n\u003ch3\u003eTechnical overview\u003c\/h3\u003e\n\n\u003cp\u003e\n  A single-use tubing assembly provides a defined fluid path between process\n  equipment, bags, bottles, filters, bioreactors and other process components.\n  The assembly can range from a simple tubing line with two end connections to\n  a complex manifold incorporating multiple branches and different fluid-path\n  components.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Tubing and components can be selected according to the required process,\n  sterilisation method and existing equipment interfaces. Suitable assemblies\n  can be configured for gamma irradiation or autoclaving, while non-sterile\n  configurations are also available.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Production and packaging take place under ISO Class 7 cleanroom conditions.\n  Components used within the assembly are inspected before cleanroom assembly,\n  and additional cleaning steps can be incorporated where required by the\n  manufacturing process.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eOperating principle\u003c\/h2\u003e\n\n\u003cp\u003e\n  The tubing assembly creates a predefined route through which process liquid\n  or gas can move between two or more points in the process. Flexible tubing\n  forms the main fluid path, while connectors, fittings, couplings, filters,\n  clamps or sanitary interfaces provide the required transitions between\n  equipment and disposable components.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  A simple assembly may connect a process vessel directly to a bag or bottle.\n  More complex configurations can divide one inlet into multiple outlets,\n  combine several process lines into a manifold or incorporate filtration,\n  sampling and filling functions within the same disposable fluid path.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Because a sterile ready-to-use assembly cannot normally be modified after\n  sterilisation without affecting its controlled condition, connection types,\n  tubing dimensions, component positions and overall layout should be defined\n  during the engineering and specification stage.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eMaterial options\u003c\/h2\u003e\n\n\u003cp\u003e\n  Tubing material is selected according to the process application, fluid\n  compatibility, sterilisation method, pump requirements and operating\n  conditions.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  The available assembly concept is not limited to one specific tubing\n  material. Different validated tubing types can be incorporated depending on\n  the process requirement.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Other fluid-path components can include plastic or sanitary fittings,\n  sterile connectors, quick couplings, filters, flanges and additional\n  process components. The material compatibility and conformity of the complete\n  assembly should be evaluated based on the final configuration.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eAvailable micron ratings\u003c\/h2\u003e\n\n\u003cp\u003e\n  \u003cstrong\u003eNot applicable to the tubing assembly itself.\u003c\/strong\u003e Flexible\n  process tubing does not have a filtration micron or pore-size rating.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Where filtration is required, a suitable filter can be incorporated directly\n  into the tubing assembly. The filter membrane, micron rating and retention\n  specification are then selected separately according to the filtration\n  requirement.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eDesign and construction\u003c\/h2\u003e\n\n\u003cp\u003e\n  Single-use tubing assemblies are manufactured according to the required fluid\n  path rather than one fixed catalogue configuration. Tubing length, branch\n  layout, connection method and integrated process components can therefore be\n  adapted to the intended application.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Different tubing-to-fitting retention methods can be used depending on the\n  mechanical and process requirements. Configurations range from simple\n  cable-tie retention through mechanical hose-retention clamps to permanent\n  overmolded transitions.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Assemblies can incorporate components such as:\n\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003eFlexible pharmaceutical and bioprocess tubing\u003c\/li\u003e\n  \u003cli\u003eAseptic and sterile connectors\u003c\/li\u003e\n  \u003cli\u003eQuick disconnect couplings\u003c\/li\u003e\n  \u003cli\u003eSanitary process connections\u003c\/li\u003e\n  \u003cli\u003eTri-Clamp interfaces\u003c\/li\u003e\n  \u003cli\u003eFilters and vent filters\u003c\/li\u003e\n  \u003cli\u003eClamps and tubing-retention components\u003c\/li\u003e\n  \u003cli\u003eManifolds and distribution branches\u003c\/li\u003e\n  \u003cli\u003eBag and bottle connections\u003c\/li\u003e\n  \u003cli\u003eBioreactor and vessel interfaces\u003c\/li\u003e\n  \u003cli\u003eOvermolded tubing connections\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\n  The exact configuration is determined by the process drawing or specification.\n  Where no existing drawing is available, the fluid path can be developed from\n  the required inlet, outlet and process functions.\n\u003c\/p\u003e\n\n\n\u003ch3\u003eSterilisation and conformity\u003c\/h3\u003e\n\n\u003cp\u003e\n  Depending on the selected tubing and fluid-path components, assemblies can be\n  supplied sterile and ready-to-use, gamma compatible, autoclavable or\n  non-sterile.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  Available conformity and production characteristics include:\n\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003eUSP Class VI\u003c\/li\u003e\n  \u003cli\u003eUSP \u0026lt;88\u0026gt;\u003c\/li\u003e\n  \u003cli\u003ecGMP-related production\u003c\/li\u003e\n  \u003cli\u003eEndotoxin statement\u003c\/li\u003e\n  \u003cli\u003eBSE\/TSE confirmation\u003c\/li\u003e\n  \u003cli\u003eIrradiation compatibility up to 40 kGy\u003c\/li\u003e\n  \u003cli\u003eAutoclavable configurations\u003c\/li\u003e\n  \u003cli\u003eISO Class 7 cleanroom production\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\n  Final conformity and sterilisation suitability should be confirmed for the\n  complete assembly because individual tubing, connectors, filters and other\n  components may have different operating and material limitations.\n\u003c\/p\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eTypical applications\u003c\/h2\u003e\n\n\u003cp\u003e\n  Custom single-use tubing assemblies are used throughout pharmaceutical and\n  biotechnology manufacturing where a defined disposable fluid path is required.\n\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003eUpstream processing\u003c\/li\u003e\n  \u003cli\u003eDownstream processing\u003c\/li\u003e\n  \u003cli\u003eFill \u0026amp; Finish\u003c\/li\u003e\n  \u003cli\u003eMedia and solution transfer\u003c\/li\u003e\n  \u003cli\u003eBuffer transfer\u003c\/li\u003e\n  \u003cli\u003eProduct transfer\u003c\/li\u003e\n  \u003cli\u003eSingle-use tubing manifolds\u003c\/li\u003e\n  \u003cli\u003eFluid distribution systems\u003c\/li\u003e\n  \u003cli\u003eSingle-use filtration sets\u003c\/li\u003e\n  \u003cli\u003eContainer and bioreactor connections\u003c\/li\u003e\n  \u003cli\u003eVent tubing assemblies\u003c\/li\u003e\n  \u003cli\u003eFilling assemblies\u003c\/li\u003e\n  \u003cli\u003ePUPSIT assemblies\u003c\/li\u003e\n  \u003cli\u003eProcess sampling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eKey benefits\u003c\/h2\u003e\n\n\u003cul\u003e\n  \u003cli\u003e\n    \u003cstrong\u003eApplication-specific configuration:\u003c\/strong\u003e\n    tubing, connections and fluid-path components can be selected according\n    to the required process.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eReady-to-use fluid paths:\u003c\/strong\u003e\n    suitable assemblies can be supplied preconfigured and sterile for direct\n    integration into the process.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eFlexible connection technology:\u003c\/strong\u003e\n    assemblies can incorporate sterile connectors, quick couplings, sanitary\n    fittings, clamps and overmolded transitions.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eSimple or complex designs:\u003c\/strong\u003e\n    configurations range from basic transfer tubing to branched manifolds,\n    filtration sets and multi-component assemblies.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eSterilisation options:\u003c\/strong\u003e\n    suitable configurations can be selected for gamma irradiation or\n    autoclaving.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eComponent flexibility:\u003c\/strong\u003e\n    different tubing, filters, connectors, couplings and flanges can be\n    incorporated according to the process requirements.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eCleanroom assembly:\u003c\/strong\u003e\n    production and packaging take place under ISO Class 7 cleanroom conditions.\n  \u003c\/li\u003e\n\n  \u003cli\u003e\n    \u003cstrong\u003eSuitable for complete single-use systems:\u003c\/strong\u003e\n    tubing assemblies can connect bags, bottles, bioreactors, filters and other\n    process equipment within one disposable fluid path.\n  \u003c\/li\u003e\n\u003c\/ul\u003e\n\n\n\u003chr\u003e\n\n\n\u003ch2\u003eConfiguration and quotation\u003c\/h2\u003e\n\n\u003cp\u003e\n  A custom single-use tubing assembly should be specified around the complete\n  fluid path. The most useful starting point is an existing assembly drawing,\n  process sketch or description of the required connections and process\n  functions.\n\u003c\/p\u003e\n\n\u003cp\u003e\n  For technical configuration and quotation, provide the following information\n  where available:\n\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003eProcess application\u003c\/li\u003e\n  \u003cli\u003eProcess fluid or gas\u003c\/li\u003e\n  \u003cli\u003eRequired tubing material\u003c\/li\u003e\n  \u003cli\u003eTubing inner diameter and outer diameter\u003c\/li\u003e\n  \u003cli\u003eRequired tubing lengths\u003c\/li\u003e\n  \u003cli\u003eNumber of branches or manifold outlets\u003c\/li\u003e\n  \u003cli\u003eRequired inlet and outlet connections\u003c\/li\u003e\n  \u003cli\u003eSterile connectors or quick couplings\u003c\/li\u003e\n  \u003cli\u003eRequired sanitary or Tri-Clamp interfaces\u003c\/li\u003e\n  \u003cli\u003eFilters or vent filters to be integrated\u003c\/li\u003e\n  \u003cli\u003eBag, bottle, vessel or bioreactor connections\u003c\/li\u003e\n  \u003cli\u003ePump application, where applicable\u003c\/li\u003e\n  \u003cli\u003eOperating temperature\u003c\/li\u003e\n  \u003cli\u003eOperating pressure\u003c\/li\u003e\n  \u003cli\u003eRequired sterilisation method\u003c\/li\u003e\n  \u003cli\u003eRequired conformity documentation\u003c\/li\u003e\n  \u003cli\u003eAnnual demand and prototype quantity\u003c\/li\u003e\n  \u003cli\u003eExisting drawing or fluid-path specification, if available\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\n  Where a complete specification is not yet available, the assembly can be\n  developed from the process requirements and required connection points.\n\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is a single-use tubing assembly?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"A single-use tubing assembly is a preconfigured disposable fluid path combining flexible process tubing with components such as connectors, couplings, filters, clamps and sanitary interfaces for pharmaceutical and bioprocess applications.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can single-use tubing assemblies be supplied sterile?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes. Suitable single-use tubing assemblies can be supplied sterile and ready-to-use. Non-sterile configurations are also available.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Can single-use tubing assemblies be gamma sterilised or autoclaved?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Assemblies can be configured using tubing and components suitable for gamma irradiation or autoclaving. 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